Semaglutide

Octadecanedioic Acid Mono-tert-butyl Ester, also known as 18-(tert-butoxy)-18-oxo-octadecanoic acid, appears as a white or off-white solid under normal conditions. It is soluble in highly polar organic solvents such as N,N-dimethylformamide but exhibits poor solubility in low-polarity solvents like diethyl ether. Additionally, it is insoluble in water.

This compound finds application in the development of long-acting and potent exendin-4-based GLP-1 analogs designed for transdermal delivery using microstructured formulations to manage blood glucose levels. As a long-chain fatty diacid, Octadecanedioic Acid Mono-tert-butyl Ester is widely employed in the synthesis of pharmaceuticals, specialty materials, and high-value-added chemicals such as fragrances. Its unique structure contributes to extending drug efficacy and optimizing pharmacokinetics in various known medicinal compounds. Increasingly, long-chain fatty carboxylic acids are being explored in drug development for their potential benefits.

CAS No: 843666-40-0

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EC No: 1592732-453-0

Application:

• Pharmaceutical Synthesis: Plays a critical role in creating long-acting GLP-1 analogs and other advanced drugs.
• Specialty Chemicals: Used in the production of high-value materials like fragrances and engineered compounds.
• Drug Development: Enhances drug efficacy and pharmacokinetics, supporting innovative therapeutic designs.
• Material Science: Integral in synthesizing specialty materials for advanced applications.

Storage condition: Sealed in dry, room temperature

Packing: Customized