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Boc-His(Trt)-Aib-Glu(OtBu)-Gly-OH
Boc-His(Trt)-Aib-Glu(OtBu)-Gly-OH is a protected pentapeptide derivative featuring a combination of Boc (tert-butyloxycarbonyl) and Trt (trityl) protecting groups. These groups safeguard functional amino acid residues, ensuring selective reactivity and stability during peptide synthesis.
The presence of Aib (α-aminoisobutyric acid) contributes rigidity to the peptide backbone, enhancing the stability of specific secondary structures. The Glu(OtBu) protection ensures the preservation of the carboxylic acid side chain of glutamic acid, while the Trt-protected histidine maintains the reactivity of its imidazole ring under controlled conditions.
CAS No: 1890228-73-5
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Application:
- Ideal for the synthesis of structured peptides and peptide analogs.
- Serves as an intermediate in pharmaceutical research and peptide-based drug discovery.
- Suitable for structural and conformational studies involving peptides with unique backbone rigidity.
Storage condition: Store in a cool, dry place, away from direct sunlight. Recommended storage temperature: 2-8°C.
Packing: Customized
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