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Boc-His(Trt)-Aib-OH

Boc-His(Trt)-Aib-OH, also known as BOC-L-HIS(TRT)-AIB-OH, is a small peptide composed of two amino acids, specifically designed for the synthesis of Somarutide. This compound combines a Boc (tert-butoxycarbonyl) protecting group on the histidine (His) residue with a trityl (Trt) group protecting the side chain of histidine, while Aib (alpha-aminoisobutyric acid) is utilized to introduce structural rigidity and stability into the peptide sequence.

The use of Boc and Trt groups provides selective protection for the amino acid residues, enabling efficient peptide bond formation during synthesis. This compound is crucial for the development of peptides like Somarutide, which require precise modifications for enhanced stability, activity, and pharmacokinetic properties.

CAS No: 2061897-68-3

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Application:

  • Peptide Synthesis: Essential for the preparation of Somarutide and other bioactive peptides.
  • Chemical Synthesis: Used as an intermediate in the creation of modified peptides with specific biological properties.
  • Research: Facilitates studies into peptide structure and function, particularly in the context of GLP-1 receptor agonists.

Storage condition: Store in a cool, dry place, away from direct sunlight. Recommended storage temperature: -20°C.

Packing: Customized

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