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Fmoc-L-Aph(L-Hor)-OH
Fmoc-L-Aph(L-Hor)-OH, also known as N-[fluorenylmethoxycarbonyl]-4-[[[(4S)-tetrahydro-2,6-dioxo-4-pyrimidinyl]carbonyl]amino]-L-phenylalanine, is an amino acid derivative used as an intermediate in pharmaceutical synthesis. This compound features an Fmoc (fluorenylmethoxycarbonyl) protective group on the amino terminus of L-phenylalanine (Aph), along with a unique side chain modification involving a tetrahydropyrimidine ring system. The modification adds complexity and functionality to the molecule, making it valuable for specific applications in peptide synthesis and drug development.
Fmoc-L-Aph(L-Hor)-OH is commonly used in the synthesis of bioactive peptides, where selective protection of functional groups is critical for maintaining stability and reactivity. The incorporation of the pyrimidine-based structure in the side chain can impart unique properties to the peptides, making this compound particularly valuable for applications in medicinal chemistry, particularly for the design of novel therapeutic peptides.
CAS No: 1253282-31-3
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Application:
- Pharmaceutical Synthesis: Used as an intermediate in the production of bioactive peptides and pharmaceutical compounds.
- Peptide Synthesis: Ideal for constructing peptides with unique structural features and biological activity.
- Drug Development: A key compound in the development of therapeutic peptides with enhanced stability and functionality.
- Biochemical Research: Supports research in the synthesis of complex peptide sequences and the exploration of peptide-based drugs.
Packing: Customized

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