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Boc-His(Boc)-Aib-Glu(OtBu)-Gly-OH
Boc-His(Boc)-Aib-Glu(OtBu)-Gly-OH is a protected pentapeptide derivative featuring Boc (tert-butyloxycarbonyl) groups for amino acid protection. This compound is commonly used in peptide synthesis, where protecting groups play a vital role in preventing undesired side reactions during stepwise assembly.
The incorporation of Aib (α-aminoisobutyric acid) adds rigidity to the peptide backbone, influencing the structural properties of the resulting peptides. The Glu(OtBu) moiety ensures protection of the carboxylic acid side chain of glutamic acid, while the doubly Boc-protected histidine provides selective reactivity for further modifications.
CAS No: 1169630-31-2
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Application:
- Intermediate for synthesizing complex peptides.
- Suitable for studies in peptide structure and function due to Aib’s influence on conformational properties.
- Utilized in pharmaceutical research and development for peptide-based drug discovery.
Storage condition: Store in a cool, dry place, away from direct sunlight. Recommended storage temperature: 2-8°C.
Packing: Customized
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