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Fmoc-Aib-OH
Fmoc-2-Amino-2-methylpropanoic acid (Fmoc-Aib-OH) is a key intermediate used in the synthesis of Enzalutamide. Enzalutamide (chemical name: 4-[3-(4-cyano-3-trifluoromethylphenyl)-5,5-dimethyl-4-oxo-2-thiomidazolidin-1-yl]-2-fluoro-N-methylbenzamide) is a second-generation non-steroidal androgen receptor (AR) antagonist, which features a novel structure. It is primarily used in the treatment of prostate cancer by blocking androgen receptors, thereby inhibiting the growth of cancer cells.
Fmoc-Aib-OH plays a crucial role in the synthesis of Enzalutamide by providing essential building blocks for peptide synthesis. The Fmoc (fluorenylmethyloxycarbonyl) group protects the amine functionality during the synthesis process, ensuring efficient and accurate incorporation into peptides.
CAS No: 94744-50-0
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EC No: 619-072-5
Application:
- Peptide Synthesis: Used as a building block in the synthesis of complex peptides and pharmaceutical intermediates.
- Enzalutamide Production: A critical intermediate in the synthesis of Enzalutamide, an androgen receptor antagonist used for prostate cancer treatment.
- Pharmaceutical Research: Essential in drug development processes, particularly in designing targeted therapies.
Storage condition: Store in a cool, dry place, away from direct sunlight. Recommended storage temperature: 2-8°C.
Packing: Customized
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