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Fmoc-D-Aph(Cbm)-OH
Fmoc-D-Aph(Cbm)-OH is a specialized amino acid derivative used in organic synthesis, particularly in peptide chemistry. This compound features an Fmoc (fluorenylmethoxycarbonyl) protecting group at the amino terminus of D-phenylalanine (D-Aph), a chiral aromatic amino acid. The side chain of the phenylalanine residue is further protected with a carbobenzyloxy (Cbm) group, which provides additional stability and selective reactivity during peptide synthesis.
Fmoc-D-Aph(Cbm)-OH is commonly employed as an intermediate in the synthesis of peptides, especially those requiring the use of D-amino acids. D-amino acids can introduce resistance to enzymatic degradation and increase the stability of peptides, making this compound valuable in the development of therapeutic peptides and bioactive molecules.
CAS No: 324017-22-3
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Application:
- Peptide Synthesis: Used as a building block for the construction of peptides that include D-amino acids for increased stability.
- Pharmaceutical Development: Ideal for synthesizing peptides with enhanced resistance to proteolysis and improved bioactivity.
- Drug Discovery: Supports the creation of peptide-based therapeutics, particularly for targeting specific biological functions.
- Biochemical Research: Useful in studying peptide stability, structure, and interactions in drug design and protein engineering.
Packing: Customized
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