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Fmoc-His(Trt)-OH

Fmoc-His(Trt)-OH, also known as N-Fmoc-N’-Trityl-L-histidine, is a derivative of L-histidine, an essential amino acid for humans. This compound features a unique imidazole side chain, which enables it to participate in a variety of chemical reactions, including the Pauly reaction, where it forms a reddish-brown compound upon reacting with diazobenzenesulfonic acid.

As a key intermediate in peptide synthesis, Fmoc-His(Trt)-OH is widely used in pharmaceutical and biochemical applications. The Trityl (Trt) group protects the imidazole side chain during synthesis, ensuring efficient and precise incorporation into peptide chains. Its high purity and stability make it an essential component for research and development in life sciences.

CAS No: 109425-51-6

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EC No: 439-640-4

Application:

  • Peptide Synthesis: A critical building block in the construction of complex peptides.
  • Pharmaceutical Research: Used to support drug development processes.
  • Biochemical Studies: Plays a role in investigating histidine’s biological activity and reactivity.

Storage condition: Store in a cool, dry place, away from direct sunlight. Recommended storage temperature: 2-8°C.

Packing: Customized

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