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Fmoc-L-Glutamic Acid 5-tert-Butyl Ester
Fmoc-L-Glutamic Acid 5-tert-Butyl Ester is a white crystalline or crystalline powder with distinct solubility properties. It dissolves readily in ethyl acetate, acetic acid, and DMF but is insoluble in petroleum ether. The compound has a melting point of 88–90°C and exhibits specific optical rotations of [α]20D -13.5° to -15.5° (0.5–2 mg/mL, DMF), [α]20D +8° (0.5–2 mg/mL, ethyl acetate), and [α]20D -4° (0.5–2 mg/mL, 80% acetic acid).
As an amino acid-protecting monomer, Fmoc-L-Glutamic Acid 5-tert-Butyl Ester is primarily employed in peptide synthesis. The tert-butyl ester group offers effective protection for the carboxylic acid functionality, allowing for precise control in synthetic pathways.
CAS No: 71989-18-9
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EC No: 276-253-8
Application:
- Peptide Synthesis: Essential for the preparation of polypeptides with high purity and structural accuracy.
- Research and Development: Used in the synthesis of amino acid derivatives and advanced biomaterials.
Storage condition: Store below +30°C.
Packing: Customized
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