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Fmoc-L-Lys[C20-OtBu-Glu(OtBu)-AEEA]-OH

Fmoc-L-Lys[C20-OtBu-Glu(OtBu)-AEEA]-OH is a specialized peptide building block used in peptide synthesis. The lysine (Lys) residue is protected with an Fmoc (9-fluorenylmethoxycarbonyl) group, while the side chain of glutamic acid (Glu) is protected by tert-butyl (OtBu) groups. The structure also incorporates a long-chain fatty acid (C20) and an aminoethoxyethanol (AEEA) spacer, offering a unique combination of properties to enhance the stability and functionality of the peptide.

This compound is highly useful in the synthesis of peptides with complex structures, where stability and selective reactivity are crucial. The long fatty acid chain improves solubility in lipophilic environments, making it ideal for drug design, particularly for peptides targeting lipid membranes or those requiring enhanced bioactivity. Additionally, the AEEA spacer contributes to the compound’s flexibility and ease of modification, offering versatility in various biochemical and pharmaceutical applications.

CAS No: 2612237-97-3

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Application:

  • Peptide Synthesis: Serves as a building block for the synthesis of peptides with specific structural properties.
  • Pharmaceutical Development: Used to design peptides with enhanced stability, targeting specific biological functions.
  • Drug Design: Facilitates the creation of peptides with improved bioactivity, particularly in lipid-based environments.
  • Biochemical Research: Supports research into peptide modifications and their interactions in drug discovery.

Packing: Customized

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