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KTcos® N-Acetylneuraminic Acid
KTcos® N-Acetylneuraminic Acid, also known as N-acylneuraminate, is one of the most widely distributed forms of sialic acid in nature. It is a crucial sugar component found in glycoproteins, glycolipids, and bacterial capsules, particularly in the cell membranes or secretions of animal cells. In glycoproteins or glycolipids, the sugar is located at the non-reducing end of the sugar side chain, where its negative charge and unique chemical structure give it various physiological specificities.
This sugar residue plays a critical role in numerous biological functions. For instance, it forms the binding site for influenza viruses on red blood cell membranes and is involved in the recognition mechanisms between plasma glycoproteins and liver cells, as well as the recognition of lymphocytes in the circulatory pathways.
KTcos® N-Acetylneuraminic Acid is synthesized through a pathway that includes N-acetylmannosamine or its 6-phosphate ester, which reacts with CTP catalyzed by specific pyrophosphatases to form CMP-N-acetylneuraminic acid. This is then incorporated into sugar chains through a glycosyl transfer reaction.
INCI Name: N-Acetylneuraminic Acid
CAS No: 131-48-6
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EC No: 205-023-1
Application: Cell Recognition, Immune System Support, Glycoprotein Stabilization, Anti-viral, Skin Health.
Storage condition: -20°C
Packing: Customized
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